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KMID : 0378019710140040132
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New Medical Journal
1971 Volume.14 No. 4 p.132 ~ p.134
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Clinical Experience on Bactrim against soft tissue infection in surgical patient
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Abstract
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To assess the effect of new antibiotics-Bactrim on severe surgical infection of the soft tissue, we selected 18 patients from the hospitalized at SNU Hospital in. 1969-1970 period. Following were the selection´ criteria
U Who showed no effectiveness on conventional antibiotics of medical or massive doses.
? Who showed resistance to known antibiotics.
? Who showed conversion to resistant strain while treatment.
Following patient were also excluded for evaluation of toxic effect of Bactrim.
1B Patient with known hepatic, renal, hematologic, digestive and dermatologic disease.
? Patient with known allergic tendencies.
Result of treatment were; good 72.2%, moderate 11. 1%, poor 11. 1%, not evaluated 5.5%.
No known severe toxic effect developed except 2 cases of nausea and 2 cases of indigestion, which were relieved with cessation of drug and antacid treatment.
Eighteen patient had previous massive antibiotic therapy, although good result were obtained among whom Bactrim was their first antibiotic used.
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